2-Ethyl-3-hydroxy-6-methylpyridine

Base Information

  • Chemical Name: 2-Ethyl-3-hydroxy-6-methylpyridine
  • CAS No.: 2364-75-2

Factory Supply industrial standard 2-Ethyl-3-hydroxy-6-methylpyridine 2364-75-2 In Stock

  • Molecular Formula: C8H11NO
  • Molecular Weight: 137.181
  • Vapor Pressure: 0.0022mmHg at 25°C 
  • Melting Point: 136-138 °C 
  • Refractive Index: 1.536 
  • Boiling Point: 280.6 °C at 760 mmHg 
  • PKA: 10.59±0.10(Predicted) 
  • Flash Point: 123.5 °C 
  • PSA： 33.12000 
  • Density: 1.053 g/cm3 
  • LogP: 1.65800 

2-Ethyl-3-hydroxy-6-methylpyridine(Cas 2364-75-2) Usage

InChI:InChI=1/C8H11NO/c1-3-7-8(10)5-4-6(2)9-7/h4-5,10H,3H2,1-2H3

2364-75-2 Relevant articles

Improved synthesis method of 6-methyl-2-ethyl-3-hydroxypyridine

-

Paragraph 0020; 0022; 0023; 0025; 0026; 0028, (2021/05/01)

The invention discloses an improved synt...

Facile one-pot direct arylation and alkylation of nitropyridine N -oxides with grignard reagents

Zhang, Fang,Duan, Xin-Fang

supporting information; experimental part, p. 6102 - 6105 (2012/01/06)

Facile arylation and alkylation of nitro...

A new method for preparation of 3-hydroxypyridines from furfurylamines by photooxygenation

Kuo,Shih

, p. 181 - 183 (2007/10/02)

-

2364-75-2 Process route

5-methyl-2-propionylfuran
10599-69-6

5-methyl-2-propionylfuran

emoxypine
2364-75-2

emoxypine

Conditions
Conditions Yield
With ammonia; toluene-4-sulfonic acid; at 170 ℃; for 5h; under 10501.1 Torr; Temperature; Pressure; Autoclave;
96.2%
With ethanol; ammonia; at 170 ℃;
Multi-step reaction with 3 steps
1: NH2 OH*HCl, NaOH / ethanol; H2 O / 0.33 h / Heating
2: Raney Ni alloy, 2 N aq. NaOH / ethanol / 1 h / Ambient temperature
3: 1.) oxygen, tetraphenylporphine, 2.) triphenylphosphine / 1.) CH2 Cl2 , -70 deg C, irradiation, 2 h, 2.) -70 deg C, 10 min
With sodium hydroxide; Raney Ni alloy; hydroxylamine hydrochloride; oxygen; 5,15,10,20-tetraphenylporphyrin; triphenylphosphine; In ethanol; water;
2-ethyl-6-methylpyridin-3-amine
1344663-48-4

2-ethyl-6-methylpyridin-3-amine

emoxypine
2364-75-2

emoxypine

Conditions
Conditions Yield
With sulfuric acid; sodium nitrite; In water; at 0 ℃; Reflux;
90%

2364-75-2 Upstream products

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2364-75-2 Downstream products

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    N-(3-Dimethylamino-propyl)-2-(2-ethyl-6-methyl-pyridin-3-yloxy)-acetamide

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    C16 H17 Cl2 NO2

  • 128228-60-4
    128228-60-4

    mexidol

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