6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate

Base Information

  • Chemical Name: 6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate
  • CAS No.: 29205-06-9

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1.What is the 6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate ?

Fluocortolone Pivalate is a glucocorticoid.

2,2-Dimethyl-propionic acid 2-((6S,10R,11R,13S,16R,17S)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl ester
25091-88-7,29205-06-9

2,2-Dimethyl-propionic acid 2-((6S,10R,11R,13S,16R,17S)-6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl ester

Conditions
Conditions Yield
Alkohol I (R=H), ClCH2CH2Cl, (Me3CCO)2O;
2,2-Dimethyl-propionic acid 2-(6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl ester
25091-88-7,29205-06-9

2,2-Dimethyl-propionic acid 2-(6-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl ester

Conditions
Conditions Yield
Entspr. 11β,21-Dihydroxy-Verb.;

2.What is the CAS number for 6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate ?

The CAS number of 6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate is 29205-06-9.

More information of 6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate 29205-06-9 are:

CAS?Number

29205-06-9

Density

1.19g/cm3

Melting Point

187 °C

Boiling Point

572.3°Cat760mmHg

Flash Point

299.9°C

Refractive Index

1.544

PSA

80.67000

LogP

4.23370

Pka

14.05±0.70(Predicted)

3.What are another words for 6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate ?

Synonyms?for?6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate 29205-06-9:Pregna-1,4-diene-3,20-dione,6a-fluoro-11b,21-dihydroxy-16a-methyl-, 21-pivalate (8CI); 6a-Fluoro-11b-hydroxy-21-trimethylacetoxy-16a-methylpregna-1,4-diene-3,20-dione;Flucortolone pivalate; Fluocortolone 21-trimethylacetate; Fluocortolonepivalate; Fluocortolone trimethylacetate

4.What is the molecular formula of 6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate?

The chemical formula of ?6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate is?C27 H37 FO5 which containing 27 Carbon atoms,37 Hydrogen atoms,1 Fluorine atoms and 5 Oxygen atoms,and the molecular weight of??6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate?is 460.586.

5.What is 6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate (29205-06-9) used for?

6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate, also known as Fluocortolone Pivalate, is a synthetic glucocorticoid derived from the pregnane class of steroid hormones. It is characterized by its white or almost white crystalline powder appearance. 6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate exhibits potent anti-inflammatory and immunosuppressive properties, making it a valuable pharmaceutical agent for various medical applications.

InChI:InChI=1/C27H37FO5/c1-14-9-17-16-11-19(28)18-10-15(30)7-8-26(18,5)23(16)21(33-24(32)25(2,3)4)12-27(17,6)22(14)20(31)13-29/h7-8,10,14,16-17,19,21-23,29H,9,11-13H2,1-6H3/t14-,16+,17+,19+,21+,22-,23-,26+,27+/m1/s1

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