N-NITROSOPYRROLIDINE

Base Information

  • Chemical Name:N-NITROSOPYRROLIDINE
  • CAS No.:930-55-2

Factory Supply Industrial Grade N-NITROSOPYRROLIDINE 930-55-2 with Best Price We provide high quality N-NITROSOPYRROLIDINE (CAS 930-55-2), at a very affordable prices to our customers.

1.What is the N-NITROSOPYRROLIDINE ?

N-Nitrosopyrrolidine (NPYR) is a nitrosamine compound that is used primarily as a research chemical and is not produced commercially. There is the possibility of generating NPYR after frying in dry-cured bacon. The major amine precursors to NPYR in cooked bacon are free proline in the adipose tissue and to a lesser extent, collagenous connective tissues. When proline peptides were heated with nitrite at pH 3.4, small amounts of NPYR were formed from all tested peptides. There are several potential sources of exposure of man to this group of potent carcinogens. Certain foods were thought to be derived from the interaction of nitrite with secondary amines in the food, either spontaneously or by the agency of bacteria. Recently the possibility that nitrosamines may be formed from secondary amines and nitrite in the gastrointestinal tract has been explored. The acid conditions that prevail in the human stomach favor the nitrosation of dimethylamine. In addition, at neutral pH, many secondary amines can be nitrosated by nitrite or nitrate in the presence of intestinal bacteria, or the cecal contents of the rat, and soluble enzymes which catalyze the N-nitrosation of several secondary amines have been extracted from two microorganisms. The rate of nitrosamine formation depends greatly on the basicity of the amine; the less basic amines such as diphenylamine and pyrrolidine are nitrosated far more readily than the strongly basic dimethylamine and diethylamine.

1-Nitrosopyrrolidine is one of the N-nitroso compounds (NOCs) implicated in human colon carcinogenesis (1,2,3) but the toxicological mechanisms involved have not been elucidated. Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.

2.What is the CAS number for N-NITROSOPYRROLIDINE ?

The CAS number of N-NITROSOPYRROLIDINE is 930-55-2.

More information of N-NITROSOPYRROLIDINE 930-55-2 are:

CAS?Number

930-55-2

Density

1.24g/cm3

Boiling Point

214°Cat760mmHg

Flash Point

83.3°C

Vapor Pressure

0.233mmHg at 25°C

Refractive Index

n20/D 1.489(lit.)

HS CODE

2933990090

PSA

32.67000

LogP

0.70150

Pka

-3.14±0.20(Predicted)

3.What is the molecular formula of N-NITROSOPYRROLIDINE ?

The chemical formula of?N-NITROSOPYRROLIDINE is C4H8 N2 O which containing 4 Carbon atoms,8 Hydrogen atoms,2 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight, and the molecular weight of N-NITROSOPYRROLIDINE is 100.12

4.What is N-NITROSOPYRROLIDINE(930-55-2)used for?

N-Nitrosopyrrolidine (NPYR) is a nitrosamine compound that is used primarily as a research chemical and is not produced commercially. There is the possibility of generating NPYR after frying in dry-cured bacon. The major amine precursors to NPYR in cooked bacon are free proline in the adipose tissue and to a lesser extent, collagenous connective tissues. When proline peptides were heated with nitrite at pH 3.4, small amounts of NPYR were formed from all tested peptides. There are several potential sources of exposure of man to this group of potent carcinogens. Certain foods were thought to be derived from the interaction of nitrite with secondary amines in the food, either spontaneously or by the agency of bacteria. Recently the possibility that nitrosamines may be formed from secondary amines and nitrite in the gastrointestinal tract has been explored. The acid conditions that prevail in the human stomach favor the nitrosation of dimethylamine. In addition, at neutral pH, many secondary amines can be nitrosated by nitrite or nitrate in the presence of intestinal bacteria, or the cecal contents of the rat, and soluble enzymes which catalyze the N-nitrosation of several secondary amines have been extracted from two microorganisms. The rate of nitrosamine formation depends greatly on the basicity of the amine; the less basic amines such as diphenylamine and pyrrolidine are nitrosated far more readily than the strongly basic dimethylamine and diethylamine.

InChI:InChI=1/C4H8N2O/c7-5-6-3-1-2-4-6/h1-4H2

Relevant articles related to N-NITROSOPYRROLIDINE:

Article

Source

Versatile new reagent for nitrosation under mild conditions

Galloway, Jordan D.,Sarabia, Cristian,Fettinger, James C.,Hratchian, Hrant P.,Baxter, Ryan D.

supporting information, p. 3253 - 3258 (2021/05/06)

5.Factory Supply Industrial Grade N-NITROSOPYRROLIDINE 930-55-2 with Best Price

tianjin xintaimei chemical co, ltd. is a quality supplier of N-NITROSOPYRROLIDINE. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on N-NITROSOPYRROLIDINE 930-55-2.

Online Inquiry
*Product Name
CAS
Purity
Quantity
Company name
*Email
*Other Description
*Code
Fields with*are required